It is the responsibility of state audit to avoid and expose the corruption, it is also the important channel for state audit to participate in state governance. This paper provides the example of Czech’s SAO. The practice and experience of Czech’s SAO participating in anti-corruption, the practice of Czech’s SAO audit in the financial revenue and expenditure of state-owned enterprise, in the contract of government procurement, in the management of EU funds and other aspects, especially the initiation of some constructive requirements on corruption prevention, can be used for reference in China’s national audit. In addition, Czech’s SAO not only increases information audit training for the staff but also actively participates in the international cooperation in anti-corruption audit to promote the level of anti-corruption audit, which has obtaineded a series of results. Hence, National Audit Office of China can learn from Czech’s SAO’s anti-corruption audit experience, in order to better participate in the state governance.