Innovation persistence is an important engine for the high-quality development of the national economy and has a significant impact on the long-term growth of the entity firms. Based on the data of China’s A-share non-financial listed companies from 2011 to 2020, this paper empirically studies the impact of digital economy on firm innovation persistence from the perspective of dual audit. The research results show that the digital economy can not only significantly promote the firm innovation persistence, but also enhance this effect through dual audit quality. Further research found that the development of digital economy plays a more significant role in promoting the innovation persistence among non-state-owned firms and small to medium-sized firms.